Upstream / Downstream Manufacturing Supervisor

Upstream / Downstream Manufacturing Supervisor Pharma Universe Chicago, IL, US 1 day ago Quick Job type Full-time Remote Quick Job description We're building a high-impact Drug Substance Manufacturing team at a brand-new, state-of-the-art site in Chicago - and looking for 2 new Manufacturing Supervisors who will lead the 2nd and 3rd shift Drug Substance teams. The appointed candidate will play a critical role in managing the production activities for Biologics Manufacturing for the 2nd or 3rd shift operation. This includes supervising cell culture fermentation, protein purification, and aseptic processing to produce high-quality drug substances. Location : City of Chicago Hours : Monday-Friday 2pm-10pm or 10pm-6am Pay : $45-$50 / hr + bonus + 1.5x overtime. Responsibilities : Lead and supervise daily production activities in compliance with cGMPs, SOPs, and Environmental Health and Safety (EHS) guidelines. Oversee E. coli cell culture fermentation, centrifugation, and homogenization processes. Manage protein purification using chromatography columns and various filtration systems. Ensure successful formulation, aseptic filtration, and visual inspection of drug product syringes. Coordinate the preparation, washing, and sterilization of machine parts and materials for aseptic processing areas. Report production status and progress to supervisors and other departments. Coordinate production batch scheduling with management, adjusting schedules as necessary to meet production needs and timelines. Implement organizational systems to efficiently allocate workload, maintain compliance, and improve productivity across shifts. Train employees on cleanroom behavior, equipment operation, and detailed process instructions. Develop and maintain comprehensive training materials and ensure staff remain up-to-date on operational protocols and compliance requirements. Author and revise Batch Records, Standard Operating Procedures (SOPs), and other production documentation to integrate cGMPs and optimize process efficiency. Ensure all manufacturing activities adhere to internal and external regulatory standards, supporting audits and inspections as needed. Participate in the qualification of drug product manufacturing suites, ensuring successful validation and qualification batch execution. Procure necessary materials and supplies with a focus on cost reduction and resource Track and manage inventory to support continuous production flow, while identifying and implementing strategies to minimize waste and reduce material costs. Identify opportunities for efficiency improvements and lead initiatives to enhance process performance. Implement best practices and support continuous improvement in production quality and throughput. Experience / Qualifications : Bachelor's degree in Biotechnology, Biochemistry, Microbiology, Chemical Engineering, or a related field. Minimum 3-5 years in biologics or biopharmaceutical manufacturing, with expertise in cell culture, fermentation, and protein purification. Hands-on experience with aseptic processing and equipment preparation. Prior experience supervising or coordinating manufacturing teams within a cGMP environment. a job alert for this search Manufacturing Supervisor Chicago, IL, US Related jobs Director of Upstream Operations Smith+Nephew US Full-time At Smith+Nephew we design and manufacture technology that takes the limits off living.The Director, Upstream Operations is a strategic and influential role within the organization, focused on align... Show more Last updated: 30+ days ago Promoted Manufacturing Engineer NSI INDUSTRIES Harwood Heights, IL, US Full-time Focused on the electrical, network infrastructure and HVAC markets, .We are all about Making Connections, and we know our future success depends on the collective talents and experiences of ou... Show more Last updated: 30+ days ago Manufacturing Supervisor (DS) 3rd Shift Kashiv BioSciences Chicago, US Full-time The Manufacturing Supervisor (DS), is a regular employee in a full-time non-exempt position at Kashiv BioSciences, LLC, in Chicago, IL.

This employee will be responsible for executing and facilitati... Show more Last updated: 30+ days ago Promoted Manufacturing Manager DSJ Global Chicago, IL, US Full-time A worldwide leader in diagnostic solutions is searching for a Manufacturing Manager to lead the team in the Chicagoland Area.

With over 50 years in medical device manufacturing, this company is cont... Show more Last updated: 30+ days ago Promoted Manufacturing Engineer Michael Page Harwood Heights, IL, US Full-time Emphasis on professional development and career advancement.Leading supplier of global aerospace clients.Our client is a privately owned manufacturer serving clients in the aerospace industry.They ... Show more Last updated: 30+ days ago Promoted Manufacturing Supervisor (DS) 3rd Shift Kashiv Biosciences LLC Chicago, IL, US Full-time The Manufacturing Supervisor (DS), is a regular employee in a full-time non-exempt position at Kashiv BioSciences, LLC, in Chicago, IL.

This employee will be responsible for executing and facilitati... Show more Last updated: 30+ days ago Promoted Manufacturing Specialist NuMat Chicago, IL, US Full-time Title : Manufacturing Specialist.Benefits include : Up to $750 / month employer contribution toward employee medical insurance, including dependent coverage, 99% employer-paid dental and vision coverag... Show more Last updated: 28 days ago Downstream Market Analyst Laborintos Chicago, Illinois, .US Full-time Quick Contamos con un equipo solido y robusto de consultores especializados en busqueda y seleccion de personal, asi como en consultoria en diversos temas asociado al Talento Humano en multiples sectores... Show more Last updated: 30+ days ago Sales Manager Downstream Valves - West USA AS-Schneider Group USA Full-time Developing and Managing the sales area,.Developing a business plan covering sales, revenue, and expense controls, meeting agreed targets, and promoting the organisation's presence throughout the re... Show more Last updated: 30+ days ago New! Manufacturing Engineer Smiths Group Elmwood Park, Illinois, USA Full-time STS Aerospace is looking for a.This is accomplished by driving continuous improvement initiatives process development / modification documentation of standards / best practices and equipment onboarding... Show more Last updated: 19 hours ago Promoted New! Upstream / Downstream Manufacturing Supervisor Pharma Universe Chicago, IL, US Full-time We're building a high-impact Drug Substance Manufacturing team at a brand-new, state-of-the-art site in Chicago - and looking for 2 new Manufacturing Supervisors who will lead the 2nd a... Show more Last updated: 6 hours ago Promoted Manufacturing Specialist Numat Chicago, IL, US Full-time Title : Manufacturing Specialist.Benefits include : Up to $750 / month employer contribution toward employee medical insurance, including dependent coverage, 99% employer-paid dental and vision coverag... Show more Last updated: 24 days ago Promoted New! Upstream / Downstream Manufacturing Supervisor Pharma Universe Chicago, IL, US Full-time We're building a high-impact Drug Substance Manufacturing team at a brand-new, state-of-the-art site in Chicago - and looking for 2 new Manufacturing Supervisors who will lead the 2nd a... Show more Last updated: 6 hours ago Manufacturing - Digital Manufacturing, Manager PricewaterhouseCoopers Advisory Services LLC Chicago,IL Full-time SummaryAt PwC, our people in operations consulting specialise in providing consulting services on optimising operational efficiency and effectiveness.

These individuals analyse client needs, develop... Show more Last updated: 30+ days ago Manufacturing Supervisor. Medtronic Rice Creek, Minnesota, US Full-time Responsibilities may include the following and other duties may be assigned.Responsible for the development and implementation of activities in production area(s) to meet production goals, quality,... Show more Last updated: 30+ days ago Manufacturing Supervisor. Medtronic Rice Creek, Minnesota, US Full-time Responsibilities may include the following and other duties may be assigned.Responsible for the development and implementation of activities in production area(s) to meet production goals, quality,... Show more Last updated: 30+ days ago CQV Engineer - Downstream Quanta part of QCS Staffing Massachusetts Full-time CQV Engineer - Downstream - Life Sciences - Contract - Massachusetts.Our client, a leading partner to pharmaceutical, biotech and nutrition markets, has an exciting opening for a CQV Engineer - Dow... Show more Last updated: 30+ days ago Technical Operations Supervisor DiaSorin Chicago, IL, United States Full-time Diasorin is a global leader in diagnostic solutions, pushing the boundaries of science and technology to create cutting-edge tools that improve healthcare worldwide.

With a legacy spanning over 50 y... Show more Last updated: 26 days ago